Evidence Synthesis Tools DirectoryA curated directory of 288+ open-source tools for systematic reviews, meta-analysis and evidence synthesis, based on a systematic mapping study. It covers the full workflow from search and screening to extraction, risk-of-bias assessment and meta-analysis, and only lists publicly available, OSI-licensed software. Web Medicine Project Research Systematic Review Open Science Research Guide evidencesynthesis-tools.github.io Mapping study Curated list of 288+ open-source evidence synthesis tools Covers search, screening, extraction, risk of bias and meta-analysis Only OSI-approved open-source software with verified public repositories Excludes proprietary and freemium tools Built to promote FAIR principles and open science